Clinical Testing With Princeton Consumer Research

Nalini Kaul MSc., Ph.D. VP Technical Services & Simon Putnam Business Development Manager at Princeton Consumer Research.

Clinical testing of products is important for ensuring products safety & efficacy and for claim substantiation. At PCR we are leaders in clinical testing and deal with the biggest brands,  as well as newcomers to the industry.

We test for safety and efficacy of your products along with substantiation of your claims that would be admissible and give you the proven edge in the market. 
PCR conducts high quality clinical trials which adds to your product’s success and provides you with an advantage over your competition.
Our global locations along with a team of highly experienced people helps design, manage, and run the clinical trial catering to each client’s individual needs. 
Our scientific expertise in understanding your needs and coming up with the most suitable design, fast recruitment strategies,  optimized study designs,  expedited trials, ensuring quality and robustness of data save you both time and money, all critical elements in ensuring your success. Robust evidence is needed for any claim you are making to satisfy customers who are becoming more savvy and demanding, we help you achieve this.

​Our services include consulting, protocol development, ethics submission, trial management, statistical analyses, report writing and quality assurance ensuring compliance to guidelines and legislations. PCR has on board dermatologists, physicians, gynaecologists, dentists, scientists, biochemists, statisticians and more to cater to your unique needs.
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Below are some of the more common studies we can help you with:

• HRIPT’s- Shared Panel (induction application patches for 24 or 48 hours)
• SPF - Sunscreens (IS FDA Monograph, Colipa Method, SPF Water resistant, ISO 24444)
• UVA Testing (ISO 24442, Broad Spectrum, ISO 24443) Boots star rating.
• Primary irritation Patch Tests (24, 48 & 96 hours)
• Follicular Biopsies for non-comedogenicity
• Safety in Use (SIU) Studies
• Dermatological, Comedogenicity, Ophthalmology, Paediatric, Gynaecological
• Ocular Instillation
• Phototoxicity (PT)
• Photo allergy (PA)
• Moisturization
• Cell Renewal - Dansyl Chloride
• Long Lasting
• Anti-Aging
• AP/Deo testing
• Dietary/Supplement Testing (in Vivo)
• Home Panel Consumer user trials
• Face Mask Trials, Long Wear, Transfer etc.
• Hair Care Full Range

​Now here are more details on one of the most popular studies available.
 
“HRIPT” stands for “Human Repeat Insult Patch Test” even though over half a century old, is a common testing method in determining irritation, allergic and sensitization potential of a product. It is a confirmatory test in safety evaluations of skin sensitizers. Typically, 50/100/200 subjects are exposed for (9x24-hour or 48-hour) over a three-week period (Induction Phase).

​After a two-week break (Rest Phase-week 4 and 5), a challenge exposure is made on both induction and a naïve site, again with a 24/48-hour patch ( Challenge Phase -week 6).

Skin reactions are scored over subsequent days. Variation in the study design include patch type, use of occlusive or semi occlusive patches, length of induction exposures and grading scales.

Advantages

HRIPT testing helps in proving that the product tested minimizes the risk of allergenic reactions and/or skin irritation on a target consumer population. As new ingredients are being added to existing topical formulations making the formulations increasingly complex, or as entirely new formulations are being introduced, the risk of being exposed to allergens is thus more frequent. Ruling out the irritation/ the allergenic potential of a product before it’s market entry therefore assumes prime importance.

Today’s savvy consumers who have all the information available at their fingertips, while seeking truthfulness and honesty of ingredients and claims on the label is also able to make an informed decision while choosing a product, backed by results of a sound clinical safety study.
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HRIPT product claims typically includes “Hypo-allergenic”, “Dermatologically tested”, Dermatologist/Paediatrician/Gynaecologist-Approved”, “Non-irritating”, “Allergen Tested”, ”Clinically Tested”, “Safe/Suitable for sensitive skin”, “Suitable for all skin types/tones” and “Safe for skin”.
 
Come to the experts at PCR for your Safety testing needs to save time and money. Phase 3 trials are expensive, and you do not want to be surprised. So, it very important to conduct the safety testing very early with your product.
 
Here at Princeton Consumer Research, we pride ourselves on being delay free at all our Global facilities, at peak times these studies are run weekly, we offer fast results within 5 days of study completion and all for a very competitive price.
 
For further information contact simonputnam@princetonconsumer.com
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